Pioneered sirtuin research, Information Theory of Aging, and the Lifespan podcast
David Sinclair is a professor of genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for Biology of Aging Research. His groundbreaking work on sirtuins and NAD+ metabolism has shaped modern understanding of aging as a treatable condition. Author of the bestselling book 'Lifespan: Why We Age and Why We Don't Have To,' he's become the public face of longevity science. His 'Information Theory of Aging' proposes that aging results from loss of epigenetic information, which can potentially be reversed. Sinclair is known for his personal protocol — daily NMN, resveratrol, metformin, time-restricted eating (skipping breakfast), and regular exercise — which he discusses publicly on his Lifespan podcast and in interviews that regularly go viral.