The best omega-3 supplement for longevity in 2026 is a triglyceride-form (rTG or natural TG) fish oil providing at least 2 grams of combined EPA + DHA per day, IFOS-certified for purity, and stored in dark glass to prevent oxidation. Higher EPA ratios are preferred for cardiovascular and cognitive longevity. Plain ethyl-ester fish oils absorb less efficiently than triglyceride-form, so the form is the single most important spec to check.

Omega-3s (EPA and DHA) are the only essential fatty acids the body cannot manufacture in meaningful quantities. They are foundational for:

Dr. Peter Attia consistently lists omega-3 fish oil as one of his top three personal supplements alongside vitamin D and magnesium.

Five criteria — weighted in this order:

1. Form: triglyceride or re-esterified triglyceride (rTG) — absorption is roughly 70% higher than ethyl ester forms.