Lactoferrin clinical trial doses span 100 mg/day (infant supplementation) to 6,000 mg/day (MRSA decolonization research), with the most common adult therapeutic range being 200–300 mg/day for immune and gut health indications and 500–1,000 mg/day for antiviral applications. No dose-response relationship has been formally characterized across the full range for aging-relevant outcomes.

Should I take lactoferrin in one dose or split it?

Single daily dose (200 mg) is used in most trials. For doses of 300+ mg/day, splitting into 2 doses (morning + evening) may improve mucosal exposure continuity. No clear evidence favors splitting vs single dosing at 200 mg.

Can I take more than 300 mg/day?

Doses up to 600 mg/day are well-tolerated in clinical studies. For specific applications (active infection, aggressive immune support), 500–1,000 mg/day is clinically studied. Above 300 mg/day, GI side effects (mild bloating, loose stools) become more common.