H. pylori requires iron for growth and colonization of the gastric mucosa. Lactoferrin's iron sequestration creates an iron-restricted environment that inhibits H. pylori proliferation. Multiple clinical trials show adding lactoferrin to standard H. pylori eradication therapy (PPI + two antibiotics) significantly improves eradication rates — particularly important given rising antibiotic resistance.

Should I use standard enteric-coated or non-enteric lactoferrin for H. pylori?

For H. pylori specifically (which lives in the stomach), non-enteric lactoferrin that releases in the stomach is preferred — allowing maximum stomach contact with both intact lactoferrin and lactoferricin active peptide.

Does lactoferrin alone clear H. pylori infection?

No. H. pylori is a resilient infection requiring antibiotic therapy for eradication. Lactoferrin significantly improves eradication rates as an adjunct but cannot clear infection without antibiotics.