NK cells recognize and kill cancer cells and virus-infected cells without prior sensitization — making them the frontline defense against cancer and viral infection. Lactoferrin binds to NK cell LfR1 receptors and activates intracellular STAT4 signaling, increasing NK cell cytotoxic granule content (granzyme B, perforin) and ADCC (antibody-dependent cellular cytotoxicity) capacity.

Does lactoferrin have cancer treatment applications?

Lactoferrin is not a cancer treatment. Its NK cell activation and ADCC enhancement properties are relevant for immune surveillance (prevention), and some researchers have proposed lactoferrin as an adjunct to cancer immunotherapy. No clinical trials have established lactoferrin as primary or adjunct cancer treatment.

How often should I take lactoferrin for cancer prevention purposes?

Daily continuous use (200–300 mg/day) is most appropriate for sustained NK cell activation support. Cancer immune surveillance is a continuous process requiring ongoing immune vigilance.