Berberine capsules, barberries and goldenseal root collage

Berberine Dose Calculator

Compare common trial doses for blood sugar or lipid goals. The estimate is not weight-based and does not replace medication advice.

How to read your result

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Your dose

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Evidence range / upper limit

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Evidence grade B

Medication & safety cautions

How this estimate works

Blood sugar goal: 1,500 mg/day as three 500 mg doses with meals. Lipid goal: 1,000 mg/day as two 500 mg doses with meals. The range shown reflects common trial totals; amounts above 1,500 mg/day need clinician oversight.

Key studies

  1. Dong et al. 2012 — Evidence-Based Complementary and Alternative Medicine · systematic review
  2. Yin et al. 2008 — Metabolism · clinical comparison in type 2 diabetes
  3. Ju et al. 2018 — Phytomedicine · randomized-trial systematic review of dyslipidaemias

Berberine buying guide · Intervention evidence

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Thorne Berberine

Best for: a standard berberine HCl product used in the buying guide

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GlucoVantage Dihydroberberine (DHB)

Best for: comparing a dihydroberberine form discussed in the guide

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Frequently asked questions

Is berberine dose based on body weight?

No. The common trial amounts shown here are fixed daily totals, not weight-based doses.

Can I combine berberine with diabetes medicine?

Berberine may add to glucose lowering and can interact with medicines. Talk with your prescriber before combining it with metformin, insulin or a sulfonylurea.

How long should I wait before checking results?

This calculator suggests discussing a repeat HbA1c or lipid test at about 12 weeks. Your clinician may recommend a different interval.

Educational tool, not medical advice. Check with your doctor, especially if you take medication.