Heart and glowing mitochondrion with CoQ10 softgels

CoQ10 Dose Calculator

Choose a context to see a commonly studied CoQ10 amount. Heart-failure dosing is a discussion for your cardiologist, not a self-treatment plan.

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Evidence grade A

Medication & safety cautions

How this estimate works

General: 100 mg/day. Statin context: 200 mg/day (2 × 100 mg). Heart failure: 300 mg/day (3 × 100 mg) only in a cardiologist-managed plan. Take with a fat-containing meal. Trials have used 100–300 mg/day; amounts up to 1,200 mg were tolerated in studies, not a suggested target.

Key studies

  1. Mortensen et al. 2014 — JACC: Heart Failure · Q-SYMBIO randomized trial
  2. Qu et al. 2018 — Journal of the American Heart Association · statin-associated muscle symptoms meta-analysis
  3. Fan et al. 2017 — Pharmacological Research · randomized-trial meta-analysis

CoQ10 buying guide · Intervention evidence

As an Amazon Associate, Stacking Years earns from qualifying purchases. This does not affect our rankings.

Jarrow Ubiquinol QH-Absorb 200mg

Best for: comparing a ubiquinol option listed in the CoQ10 guide

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Life Extension Super Ubiquinol CoQ10 200mg

Best for: comparing a CoQ10 product with PQQ listed in the guide

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Qunol Mega Ubiquinol 100mg

Best for: comparing an ubiquinol option listed in the guide

View on Amazon

Frequently asked questions

Should I take CoQ10 with a statin?

Evidence for routine use to prevent statin symptoms is mixed. Talk with your prescriber before adding it or changing a statin.

Can I use the heart-failure amount on my own?

No. The 300 mg amount comes from a clinical heart-failure trial and is for discussion with a cardiologist, not self-treatment.

Does CoQ10 need to be taken with food?

The guide recommends taking it with a fat-containing meal. Follow the specific product label and your clinician's instructions.

Educational tool, not medical advice. Check with your doctor, especially if you take medication.