NOW Foods Glycine 1000mg Capsules
Best for: the glycine component discussed in the GlyNAC guide
Glycine Dose Calculator
Choose bedtime glycine or the GlyNAC protocol. Only the GlyNAC option is weight-based, and its trial amounts are capped here at 100 kg.
How to read your result
- Start with Your dose and How to split; this is a comparison point, not a prescription.
- Check the Evidence range / upper limit and safety cautions.
- Weight, age and sex are not dose inputs unless the result explicitly says they are.
Estimate
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Your dose
Enter a valid weight
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How to split
See your serving pattern
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Evidence range / upper limit
Check the method below
Next step
Action
Review the safety notes
Is this based on your weight? Enter a valid weight to see whether this estimate uses it.
Evidence grade B
Medication & safety cautions
- NAC can interact with nitroglycerin and may aggravate asthma in some people; ask a clinician or pharmacist.
- Glycine may interact with clozapine. Discuss the combination with the prescriber.
How this estimate works
Sleep goal: 3 g glycine once, 30–60 minutes before bed; this is a fixed amount, not a weight-based dose. GlyNAC goal: the Baylor trials used glycine 100 mg/kg/day plus NAC 133 mg/kg/day, divided into two doses with meals. The calculator caps the weight used for this calculation at 100 kg. The range shown is 3–9 g/day glycine used in studies; it is not a universal target.
Key studies
- Yamadera et al. 2007 — Sleep and Biological Rhythms · glycine and subjective sleep quality
- Kumar et al. 2021 — Clinical and Translational Medicine · pilot GlyNAC trial in older adults
- Kumar et al. 2023 — The Journals of Gerontology: Series A · randomized GlyNAC trial
GlyNAC trial protocol · Intervention evidence
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Jarrow Formulas NAC 600mg Capsules
Best for: the NAC component discussed in the GlyNAC guide
Pure Encapsulations NAC + Glycine Powder
Best for: a combined powder option listed in the GlyNAC guide
Frequently asked questions
Is the sleep amount based on my weight?
No. The bedtime option is a fixed 3 g amount from a small sleep study. The separate GlyNAC option is weight-based.
Why does the GlyNAC option include NAC?
The Baylor protocol studied glycine together with N-acetylcysteine. The calculator shows both components rather than presenting glycine alone as the protocol.
Can I use the GlyNAC amount during pregnancy or breastfeeding?
Safety data are insufficient for this calculator to provide a dose. Ask your clinician.
Educational tool, not medical advice. Check with your doctor, especially if you take medication.