Quercetin and Fisetin: Natural Senolytic Compounds for Longevity

Learn how quercetin and fisetin may clear senescent cells and their potential role in anti-aging protocols.

Quercetin and fisetin have emerged as the most promising natural senolytic compounds—substances that selectively eliminate senescent "zombie" cells that accumulate with age and contribute to inflammation and tissue dysfunction. Understanding how these compounds work and how to use them appropriately could be important for longevity.

Senescent cells are cells that have stopped dividing but do not die:

Senescent cells secrete inflammatory factors that:

Senolytics selectively kill senescent cells while sparing healthy cells:

Quercetin is a flavonoid found naturally in: