Estimated longevity benefit: +0.8 years. Evidence score: 80/100.
Periodontal disease is a source of chronic systemic inflammation — oral bacteria such as Porphyromonas gingivalis enter the bloodstream and trigger inflammatory cascades that raise cardiovascular risk by 20–40% and are directly linked to Alzheimer's pathology in brain tissue. Maintaining excellent oral hygiene through brushing, flossing, and professional cleanings is one of the most consistently underestimated longevity interventions because its mechanism is fundamentally one of inflammation management rather than dental aesthetics.