Lactoferrin dosing varies considerably based on the intended clinical application. The evidence base spans doses from 100 mg/day (pediatric use, iron supplementation in pregnancy) to 1,200 mg/day (experimental cancer applications). For the vast majority of healthy adults using lactoferrin as a longevity, immune, or gut health supplement, 200-300 mg/day is well-supported and cost-effective.

| Application | Evidence-Based Dose | Source |

| Adult immune support | 200-300 mg/day | Multiple RCTs |

| Gut health (IBD, IBS) | 300-600 mg/day | Gastroenterology trials |

| Iron supplementation | 200-400 mg/day | Paesano et al. 2010 |