How much life expectancy can Vitamin C + E supplementation add?

Based on population-weighted modelling, Vitamin C + E supplementation is associated with an estimated +0.4 years of life expectancy on average. Individual results depend on baseline health, adherence level, and age of intervention.

What is the evidence score for Vitamin C + E supplementation?

Vitamin C + E supplementation has an overall evidence score of 42/100 on Stacking Years, based on a weighted combination of 5 peer-reviewed studies (85% weight) and expert consensus (15% weight).

Which longevity experts recommend Vitamin C + E supplementation?

Vitamin C + E supplementation is endorsed or discussed by longevity experts including Peter Attia, MD, Rhonda Patrick, PhD, Mark Hyman, MD. See their full protocols and citations on Stacking Years.

Is Vitamin C + E supplementation safe?

Vitamin C + E supplementation is a supplement. Safety depends on individual health status, dosing, and interactions with medications. Always consult a qualified healthcare provider before starting any new health protocol.

Vitamin C + E supplementation

Estimated longevity benefit: +0.4 years. Evidence score: 42/100.

Combined antioxidant therapy utilizes the synergistic relationship between water-soluble vitamin C and fat-soluble vitamin E to neutralize reactive oxygen species across different cellular compartments. Emerging longitudinal evidence suggests that high-dose combined supplementation may significantly reduce the risk of neurodegenerative decline by protecting neuronal membranes from oxidative damage.